Couponing services dedicated to city-specific offers are a great way to try new things and save money. Here is a video on how they work: http://vimeo.com/2112924 Living Labs posted a great summary of the services available:
Here in San Francisco, we have at least nine of the services including Groupon, HomeRun, BloomSpot, LivingSocial, Liquor.com, TownHog, Special Deals, Joffer, and Zozi. Predictably, this market expansion has created a new market: aggregation services. Yipit and LocalOfferLounge allow you to sign up for just one daily email containing all the local deals that pertain to your categorical interests (restaurants, yoga, spas, city tours, etc.).
Given how many there are to review (Social Buy is another such service), the aggregators such as Yipit and Local Offer Lounge appear to be a relatively efficient way to quickly scan them all. They will probably pick up new services as they crop up so you won't have to deal with signing up for more emails.
Groupon is the only service I've actually tried and so far so good - I've purchased and successfully used Duck Tour tickets for some recent out of town visitors and a restaurant Groupon.
A summary of some of the daily deals on offer will now be available, updated via RSS on the SF Daily Deals page - enjoy!